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Dozens dead in pharmaceutical factory blast in India

03-07-2025

Bureau Report

NEW DELHI: As many as 39 people have been confirmed dead after a powerful explosion triggered a fire at a pharmaceutical factory in the southern Indian state of Telangana.

“The condition of the bodies is such that we’ve had to deploy a specialized medical team to carry out DNA tests,” said Health and Medical Cabinet Minister of Telangana Damodar Raja Narasimha on Tuesday.

A government panel has been formed to investigate the cause of the disaster.

The blast, which erupted on Monday afternoon at a facility run by Sigachi Industries, took place in the plant’s spray dryer unit, a section used to convert raw materials into powder for drug manufacturing. The factory is located roughly 50km (31 miles) from Hyderabad, the state capital.

Authorities recovered 35 bodies from the debris, while two more workers succumbed to injuries in hospital, according to Telangana’s fire services director, GV Narayana Rao.

“The entire structure has collapsed. The fire is under control and we’re continuing to clear the rubble in case more people are trapped,” he told media.

Twenty-five of the deceased are yet to be identified, a district administrative official, P Pravinya, said. About 36 workers remain in hospital with burns and other injuries. Police officials said that more than 140 people were working in the plant when the incident occurred.

Local residents reported hearing the blast from several kilometres away.

The incident has raised new concerns about industrial safety in India’s booming pharmaceutical sector. Despite the country’s reputation as a global supplier of low-cost medicines and vaccines, fatal accidents at drug manufacturing units are not rare, particularly in facilities handling chemicals or solvents.

Sigachi Industries, which has its headquarters in India, produces active pharmaceutical ingredients and nutrient blends, and operates manufacturing plants across the country. It also runs subsidiaries in the United Arab Emirates and the United States, according to its website.

Officials say rescue and recovery efforts will continue until the entire site has been cleared. The factory’s operations have been suspended pending the outcome of the investigation.

Sigachi, which makes microcrystalline cellulose (MCC), caters to clients in the pharma, food, cosmetic and specialty chemicals sectors in countries ranging from the US to Australia.

MCC’s compressibility, binding properties, and ability to boost drug release make it a vital ingredient in pharmaceutical manufacturing. It is also used to prevent the formation of lumps in food products, to maintain texture of cosmetic products, and as a fat substitute in low-calorie foods.

Sigachi’s Telangana plant contributes a little over a fourth of its total capacity of 21,700 million metric tons per annum.

Its shares dropped about 8% on Tuesday and were headed for their sharpest two-day drop on record.

Sigachi halted operations at the plant for 90 days from Monday citing damage to equipment and structures. The plant is fully insured and the company is initiating claims.

In a separate incident on Tuesday, five people were killed and four others injured in a massive fire at a crackers factory in the Sivakasi manufacturing cluster in the southern Tamil Nadu state, a fire department official said. The incident is the latest in a series of fire accidents in the area.

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